Arne Slot's team had successfully kept a clean sheet in every league match this season, until Hudson-Odoi came off the Forest bench. With Nuno Espirito Santo calling the shots, Forest pulled off a shocking 1-0 victory.
The substitute scored the winner in the 72nd minute after Liverpool's retreating backline offered him the time and space to measure a shot from 20 yards, beckoned to try his luck by the travelling support behind the goal. He obliged, bending a perfectly precise strike beyond Alisson at full stretch.
"We lost the ball so many times in simple positions," Slot said. "It wasn't good enough, too many individual performances were not of the standard I'm used to. It's a big setback."
Liverpool, with lofty ambitions in Slot's first season in charge, created plenty but lacked any cutting edge as every final pass or attempted finish failed to hit the correct mark.
TrendingTheir 14 shots at goal - five on target - were a sign of the home side's obvious dominance, but unlike the opening three weeks of the campaign where they scored seven times, were unable to convert such superiority into anything tangible.
Meanwhile, everything Forest did paid off.
Both team selection - Ryan Yates and James Ward-Prowse were among four changes, selected to pack the middle of the park - and formation worked to stifle and frustrate Liverpool. Substitutions worked perfectly with Anthony Elanga and Hudson-Odoi combining for the winner. Game plan executed to perfection.