Alisson Becker has suffered a hamstring injury and is anticipated to be out of action until after the upcoming international break in November.
This means Liverpool will be without their No 1 goalkeeper until November.
He is expected to miss matches against Chelsea, Arsenal, Brighton, and Aston Villa in the Premier League, as well as two Champions League fixtures against RB Leipzig and Bayer Leverkusen.
Liverpool also face Brighton in the Carabao Cup, but Kelleher featured in the last round.
He was substituted in the second half of Liverpool's 1-0 win over Crystal Palace at Selhurst Park on Saturday. With regular No 2 Caoimhin Kelleher unavailable through illness, 23-year-old Vítezslav Jaros made his Premier League debut, keeping a clean sheet.
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